Used in immunological research to study natural killer (NK) cell and T-cell functions due to its role in cell adhesion and signaling. The Fc tag enables easy detection and purification, making it valuable in immunoassays, flow cytometry, and binding studies. Commonly applied in developing and testing therapeutic antibodies, especially in preclinical models involving non-human primates. Supports investigation of neurodevelopment and cancer immunotherapy, where CD56 expression correlates with cell activation and tumor progression.