Used in immunological research to study the interleukin-1 signaling pathway in non-human primate models. Facilitates the development and testing of therapeutic agents targeting inflammatory diseases, as it mimics the human IL-1 receptor accessory protein function. Commonly employed in binding assays, protein-protein interaction studies, and antibody validation due to its high purity and specific tag configuration. Supports preclinical evaluation of biologics where cross-reactivity with macaque immune systems is required.