Used in immunological research to study natural killer (NK) cell regulation and immune checkpoint mechanisms. This protein helps investigate interactions between NKG2A and its ligand CD94, which play a role in modulating NK and T cell activity. Due to its Fc tag, it can be used in binding assays, protein purification, and detection methods such as ELISA, flow cytometry, and immunoprecipitation. It is also employed in therapeutic development, particularly in cancer immunotherapy, where blocking NKG2A may enhance immune response against tumors. Commonly used in non-human primate models to support preclinical studies.