Used in immunological research to study mesothelin-related pathways and immune responses in non-human primate models. Serves as a critical reagent in developing and testing targeted therapies, particularly for cancers where mesothelin is overexpressed, such as mesothelioma and ovarian cancer. The Fc tag enables easy detection and purification, and supports assays involving immune cell engagement, including ADCC and CDC studies. Plays a role in validating therapeutic antibodies and assessing cross-reactivity before human clinical trials.