Used in immunological research to study the interleukin-6 signaling pathway in non-human primates, particularly in preclinical development of anti-inflammatory therapeutics. Serves as a critical reagent for binding assays, antibody detection, and receptor-ligand interaction studies due to its high affinity and specificity. The His Tag enables easy purification and detection, making it valuable in protein expression and characterization workflows. Commonly employed in the development and testing of biologics targeting IL-6 receptors, especially in models of autoimmune diseases and inflammation.