Used in immunological research to study angiogenesis and immune responses in primate models. The His-tag facilitates protein purification and detection, making it valuable for assays involving protein-protein interactions and receptor-ligand binding studies. Commonly applied in the development and testing of therapeutic antibodies targeting CLEC14A, particularly in cancer immunotherapy research. Supports investigation of endothelial cell function and tumor vasculature due to CLEC14A's role in vascular biology.