Used in immunological research to study Glypican-3 (GPC3) expression and function in non-human primate models, particularly for evaluating GPC3-targeted therapies in cancer, such as hepatocellular carcinoma. The Fc tag enables detection, purification, and potential immune cell engagement in assay systems, supporting development of monoclonal antibodies and immunotherapies. Commonly applied in ELISA, flow cytometry, and binding affinity studies to assess interactions with therapeutic candidates.