Used in immunological research to study the function and signaling of the GUCY2C receptor in non-human primate models, particularly in the context of intestinal physiology and immune responses. The Fc tag enables easy detection and purification, making it valuable for binding assays, antibody development, and investigating cross-reactivity with therapeutic agents targeting the GUCY2C pathway. Also employed in preclinical studies to assess drug efficacy and safety in translational research related to gastrointestinal diseases and cancer immunotherapy.