Used in immunological research to study dendritic cell function and immune response regulation. Facilitates the investigation of pathogen recognition mechanisms due to its role in pattern recognition receptor signaling. Employed in protein-protein interaction studies, particularly in understanding ligand binding within the C-type lectin receptor family. Commonly utilized in ELISA, flow cytometry, and pull-down assays to detect and quantify interacting molecules. Supports development of therapeutic strategies targeting innate immunity pathways. The His Tag allows for efficient purification and detection in recombinant expression systems.