Used in immunological research to study the function of CLEC14A, a protein involved in angiogenesis and immune regulation. The Fc tag enables easy detection and purification, making it valuable in binding assays and protein-protein interaction studies. Commonly applied in developing and testing therapeutic antibodies targeting endothelial cells, especially in cancer and inflammatory disease models. Supports assay development for evaluating drug candidates in non-human primate systems due to species compatibility.