Used in immunological research to study granulocyte-macrophage colony-stimulating factor signaling in non-human primate models. Supports the differentiation and proliferation of hematopoietic precursor cells, particularly in the development of dendritic cells and macrophages for vaccine and cancer immunotherapy studies. The His tag facilitates easy detection and purification in experimental assays. Commonly employed in in vitro cell culture systems to evaluate immune cell activation and cytokine responses relevant to human disease models.