Used in immunological research to study T-cell activation and modulation, particularly in non-human primate models. The CD3g subunit plays a critical role in T-cell receptor complex signaling, and the Fc tag enables easy detection, purification, and potential engagement of immune effector functions. Commonly applied in assays involving flow cytometry, ELISA, and protein-protein interaction studies to evaluate therapeutic antibodies or immune responses in preclinical models. Also useful for generating immune cell depletion or activation reagents in translational research.