Used in immunological research to study T cell activation and modulation in non-human primate models. Facilitates the development and testing of therapeutic antibodies, immune checkpoint inhibitors, and T cell-based therapies due to its role in the CD3 complex, which is critical for T cell receptor signaling. The His Tag allows for easy detection and purification in experimental assays. Commonly employed in ELISA, flow cytometry, and protein-protein interaction studies to evaluate immune responses and drug efficacy in preclinical studies.