Used in immunological research to study CD38 expression and function in non-human primate models, particularly in immune cell activation, signaling pathways, and development of therapeutic antibodies. The Fc tag enables easy detection, purification, and potential modulation of immune effector functions in vitro and in vivo. Commonly applied in preclinical studies for evaluating CD38-targeted therapies, such as those developed for hematological malignancies and autoimmune diseases, due to the close homology between primate and human CD38.