PIT-1 is primarily used in biological and medical research as a transcription factor involved in the regulation of pituitary gland development and hormone production. It plays a crucial role in the expression of genes that code for growth hormone, prolactin, and thyroid-stimulating hormone. Researchers study PIT-1 to understand its function in endocrine disorders, such as growth hormone deficiencies or pituitary tumors. Additionally, it is utilized in genetic studies to explore mutations that may lead to congenital hypopituitarism, providing insights into potential therapeutic targets for treating related conditions.