MCOPPB triHydrochloride is a potent and selective antagonist of the orexin-2 (OX₂) receptor, primarily utilized in biochemical and pharmacological research to study sleep-wake regulation, feeding behavior, and related physiological processes. It enables researchers to investigate the roles of orexin signaling in various conditions, including neurological disorders such as narcolepsy. This compound is often employed in experiments aimed at understanding the mechanisms underlying these disorders by modulating OX₂ receptor activity. Additionally, MCOPPB triHydrochloride is used in drug development studies to screen for potential therapeutic agents targeting orexin pathways. Its high selectivity makes it a valuable tool for elucidating complex biological interactions and advancing targeted treatments for sleep and neurological conditions.