Used in neutron absorption applications, particularly in nuclear reactors where it serves as a burnable poison to control reactivity over time. Its high neutron capture cross-section makes it effective in managing neutron flux and maintaining stable reactor operation. Also employed in research settings for neutron detection and shielding. In solid form, Ho compounds are used in magnets and laser materials due to their strong magnetic and optical properties. Additionally, Ho solutions are utilized in medical applications, including targeted radiotherapy and as contrast agents in magnetic resonance imaging (MRI) when chelated properly.