4,8-Dichloro-2-methylquinoline is primarily used in the synthesis of pharmaceuticals and agrochemicals. Its quinoline structure makes it a valuable intermediate in the development of compounds with biological activity. In the pharmaceutical industry, it is utilized to create drugs targeting infectious diseases, particularly those caused by bacteria and parasites. The compound's chlorinated and methylated groups enhance its reactivity, allowing it to be incorporated into complex molecules with therapeutic properties.

In agrochemical applications, 4,8-Dichloro-2-methylquinoline serves as a building block for the production of pesticides and herbicides. Its chemical structure contributes to the efficacy of these products in controlling pests and weeds, thereby improving crop yields. Additionally, it is employed in research and development for designing new chemical entities with potential applications in various fields, including material science and organic synthesis.