6-fluoroquinoline-4-carboxylic acid
95%
Reagent
Code: #188265
CAS Number
220844-73-5
science Other reagents with same CAS 220844-73-5
blur_circular Chemical Specifications
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Molecular Information
Weight
191.1500 g/mol
Formula
C₁₀H₆NO₂F
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Registry Numbers
MDL Number
MFCD09259934
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Storage & Handling
Storage
2-8°C, dry, sealed
description Product Description
Used as a key intermediate in the synthesis of fluoroquinolone antibiotics, which are broad-spectrum antimicrobial agents. It plays a critical role in constructing the core structure of pharmaceuticals targeting DNA gyrase and topoisomerase IV in bacteria, making it valuable in developing drugs for treating urinary tract infections, respiratory infections, and other bacterial diseases. Its fluorinated quinoline scaffold enhances cell penetration and binding affinity to bacterial enzymes, improving drug efficacy. Also explored in medicinal chemistry for developing new anti-infective and anticancer agents due to its favorable pharmacokinetic properties and ability to be functionalized at multiple positions.
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