8-Chloro-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid Ethyl Ester
97%
Reagent
Code: #165333
CAS Number
52980-27-5
blur_circular Chemical Specifications
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Molecular Information
Weight
251.67 g/mol
Formula
C₁₂H₁₀ClNO₃
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of fluoroquinolone antibiotics, particularly in the production of advanced antimicrobial agents. Its structure allows for further functionalization at the 7-position, enabling the development of compounds with enhanced activity against Gram-negative and Gram-positive bacteria. Commonly employed in pharmaceutical research to build quinolone cores, which are critical for DNA gyrase and topoisomerase IV inhibition. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies to optimize potency, spectrum, and pharmacokinetic properties of new antibiotic candidates.
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