Used as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly in targeted cancer therapies. It plays a role in blocking signaling pathways that promote tumor growth, especially in non-small cell lung cancer and other solid tumors. Its structure allows for strong binding to mutant forms of EGFR, making it valuable in developing drugs resistant to first-generation inhibitors. Also utilized in research for optimizing selectivity and reducing off-target effects in kinase inhibitor design.