Used as an intermediate in the synthesis of quinoline-based pharmaceutical compounds, particularly in the development of antimalarial and antimicrobial agents. Its structure supports binding to biological targets involved in pathogen replication, making it valuable in medicinal chemistry research. Also employed in the preparation of kinase inhibitors for potential use in cancer therapy. Commonly utilized in laboratory settings for structure-activity relationship (SAR) studies due to its electron-withdrawing and hydrogen-bonding features.