2-Chloro-4-((6,7-dimethoxyquinolin-4-yl)oxy)aniline
95%
Reagent
Code: #163700
CAS Number
286371-44-6
blur_circular Chemical Specifications
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Molecular Information
Weight
330.77 g/mol
Formula
C₁₇H₁₅ClN₂O₃
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Registry Numbers
MDL Number
MFCD28405970
thermostat
Physical Properties
Boiling Point
491.8±45.0 °C(Predicted)
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Storage & Handling
Density
1.325±0.06 g/cm3(Predicted)
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly in anticancer drug development. It plays a critical role in constructing targeted therapies for cancers such as non-small cell lung cancer and chronic myeloid leukemia. Its structure enables selective binding to mutant kinase domains, improving drug specificity and reducing off-target effects. Also employed in medicinal chemistry research to develop new analogs with enhanced potency and pharmacokinetic profiles.
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