8-Chloro-6,7-difluoro-1-((1R,2S)-2-fluorocyclopropyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
97%
science Other reagents with same CAS 127199-27-3
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description Product Description
Used as a key intermediate in the synthesis of fluoroquinolone antibiotics, particularly in the development of advanced antimicrobial agents targeting drug-resistant bacterial strains. Its structure enables enhanced penetration into bacterial cells and improved binding to DNA gyrase and topoisomerase IV, making it valuable in creating potent inhibitors. This compound is especially relevant in the design of next-generation antibiotics with broad-spectrum activity and reduced susceptibility to common resistance mechanisms. It is also employed in medicinal chemistry research to explore structure-activity relationships in quinolone-based therapeutics.
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