4-Bromoquinoline-8-carbonitrile
95%
science Other reagents with same CAS 1020743-28-5
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description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and antimalarial agents. Its structure allows for selective functionalization, making it valuable in medicinal chemistry for building complex heterocyclic systems. Commonly employed in cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations to introduce aryl or amino groups. Also utilized in the preparation of fluorescent probes due to the inherent photophysical properties of the quinoline core. Its nitrile and bromo functionalities provide dual sites for derivatization, enabling its use in combinatorial chemistry and drug discovery research.
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