2,8-Bis(trifluoromethyl)-4-hydroxyquinoline

98%

Reagent Code: #143129
label
Alias 2,8-bis(trifluoromethyl)-4-hydroxyquinoline
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CAS Number 35853-41-9

science Other reagents with same CAS 35853-41-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 281.15 g/mol
Formula C₁₁H₅F₆NO
badge Registry Numbers
EC Number 252-762-0
MDL Number MFCD00075091
thermostat Physical Properties
Melting Point 130-134 °C(lit.)
inventory_2 Storage & Handling
Storage Room temperature

description Product Description

Used as a key intermediate in the synthesis of antimalarial drugs, particularly in the development of quinoline-based derivatives that target drug-resistant strains of Plasmodium. Its trifluoromethyl groups enhance metabolic stability and membrane permeability, improving the pharmacokinetic profile of the final drug compound. Also employed in research for antimicrobial and anticancer agents due to its ability to intercalate DNA and inhibit topoisomerase enzymes. Shows promise in agrochemical applications as a fungicidal agent in crop protection.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿154.00
inventory 5g
10-20 days ฿418.00
inventory 25g
10-20 days ฿3,230.00
inventory 100g
10-20 days ฿12,020.00
inventory 500g
10-20 days ฿46,790.00

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2,8-Bis(trifluoromethyl)-4-hydroxyquinoline
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Used as a key intermediate in the synthesis of antimalarial drugs, particularly in the development of quinoline-based derivatives that target drug-resistant strains of Plasmodium. Its trifluoromethyl groups enhance metabolic stability and membrane permeability, improving the pharmacokinetic profile of the final drug compound. Also employed in research for antimicrobial and anticancer agents due to its ability to intercalate DNA and inhibit topoisomerase enzymes. Shows promise in agrochemical app

Used as a key intermediate in the synthesis of antimalarial drugs, particularly in the development of quinoline-based derivatives that target drug-resistant strains of Plasmodium. Its trifluoromethyl groups enhance metabolic stability and membrane permeability, improving the pharmacokinetic profile of the final drug compound. Also employed in research for antimicrobial and anticancer agents due to its ability to intercalate DNA and inhibit topoisomerase enzymes. Shows promise in agrochemical applications as a fungicidal agent in crop protection.

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