Used as a key intermediate in the synthesis of fluorinated quinazoline-based pharmaceuticals, particularly in the development of kinase inhibitors for cancer treatment. Its electrophilic aromatic ring allows selective substitutions at the 4-position, enabling the attachment of amino or other functional groups to build active drug molecules. Commonly employed in research settings for designing compounds with antitumor, antiviral, and anti-inflammatory activities. The presence of both fluoro and nitro groups enhances reactivity and binding selectivity in biological systems, making it valuable in medicinal chemistry for structure-activity relationship studies.