6-Chloro-8-fluoroquinazolin-4(1H)-one
98%
Reagent
Code: #163767
CAS Number
187805-51-2
blur_circular Chemical Specifications
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Molecular Information
Weight
198.58 g/mol
Formula
C₈H₄ClFN₂O
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Registry Numbers
MDL Number
MFCD30718385
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of fluorinated quinazoline derivatives, which show significant biological activity, particularly in anticancer and antimicrobial agents. Its structure allows for selective substitutions at the 4-position, enabling the development of targeted kinase inhibitors. Commonly employed in pharmaceutical research for designing drugs that modulate enzyme activity, especially in tyrosine kinase and EGFR inhibitor pathways. Also utilized in agrochemicals for developing herbicides and pesticides due to its stability and reactivity profile.
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