4-Chloroquinazolin-2-amine
98%
Reagent
Code: #162757
CAS Number
124309-74-6
blur_circular Chemical Specifications
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Molecular Information
Weight
179.61 g/mol
Formula
C₈H₆N₃Cl
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Registry Numbers
MDL Number
MFCD10697893
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. It serves as a building block in the preparation of active pharmaceutical ingredients (APIs) targeting epidermal growth factor receptor (EGFR) and other tyrosine kinases. Its structure allows for selective modification, enabling optimization of drug potency and selectivity. Also employed in research for antimalarial and anti-inflammatory agents due to its quinazoline core, which exhibits diverse biological activity. Commonly utilized in medicinal chemistry for structure-activity relationship (SAR) studies.
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