7-Chloro-N-(3-chloro-4-fluorophenyl)-6-nitroquinazolin-4-amine
97%
Reagent
Code: #161827
CAS Number
179552-73-9
blur_circular Chemical Specifications
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Molecular Information
Weight
353.14 g/mol
Formula
C₁₄H₇Cl₂FN₄O₂
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Registry Numbers
MDL Number
MFCD19440823
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Physical Properties
Boiling Point
503.3±50.0°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, protected from light, stored in inert gas
description Product Description
Used as a key intermediate in the synthesis of epidermal growth factor receptor (EGFR) inhibitors, particularly in targeted cancer therapies. Its structure enables selective binding to mutant forms of EGFR, making it valuable in the development of anticancer drugs, especially for non-small cell lung cancer (NSCLC). The compound's nitro and chloro functional groups facilitate further chemical modifications, allowing optimization of pharmacokinetic properties in drug design. It is primarily employed in research and pharmaceutical development rather than direct therapeutic use.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | Solid |
| Purity (%) | 96.5-100% |
| Infrared Spectrum | Conforms to Structure |
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