2-Chloro-6-fluoroquinazolin-4(3H)-one
95%
Reagent
Code: #160260
CAS Number
769158-12-5
blur_circular Chemical Specifications
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Molecular Information
Weight
198.58 g/mol
Formula
C₈H₄ClFN₂O
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Registry Numbers
MDL Number
MFCD11520685
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Physical Properties
Boiling Point
339.8°C
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of quinazoline-based pharmaceuticals, particularly in the development of kinase inhibitors for cancer treatment. Its structure allows for selective substitution at multiple positions, making it valuable in medicinal chemistry for optimizing drug potency and selectivity. Commonly employed in the preparation of epidermal growth factor receptor (EGFR) inhibitors. Also utilized in research settings to explore new bioactive molecules with potential antitumor, anti-inflammatory, or antimicrobial properties.
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