8-Bromo-2-chloroquinazoline
98%
Reagent
Code: #144522
CAS Number
956100-63-3
blur_circular Chemical Specifications
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Molecular Information
Weight
243.49 g/mol
Formula
C₈H₄BrClN₂
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Registry Numbers
MDL Number
MFCD11043845
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Storage & Handling
Storage
2-8°C, Inert Gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. It serves as a building block in medicinal chemistry due to its reactive halogen sites, which allow for selective cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations. Commonly employed in the preparation of bioactive quinazoline derivatives with potential antitumor, anti-inflammatory, and antimicrobial properties. Also utilized in research settings to design and optimize new drug candidates targeting tyrosine kinase and other enzyme systems.
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