3-Bromo-pyrrolo[1,2-a]pyrimidine-6-carboxylic acid
96%
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This chemical is primarily utilized in the field of medicinal chemistry as a key intermediate in the synthesis of biologically active compounds. It serves as a building block for the development of pharmaceutical agents, particularly in the design of small molecule inhibitors targeting specific enzymes or receptors. Its pyrrolo[1,2-a]pyrimidine core structure, featuring a bromo substituent at the 3-position and a carboxylic acid group at the 6-position, is often incorporated into molecules with potential therapeutic applications, such as anti-cancer, anti-inflammatory, or antiviral drugs. The carboxylic acid enables further derivatization through esterification or amide coupling, while the bromo allows for functionalization via various cross-coupling reactions. Additionally, it is employed in research settings for the exploration of structure-activity relationships (SAR) to optimize drug efficacy and selectivity, making it a versatile component in organic synthesis.
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