5-(4-aminophenyl)-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
95%
Reagent
Code: #196532
CAS Number
1770824-08-2
blur_circular Chemical Specifications
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Molecular Information
Weight
239.28 g/mol
Formula
C₁₃H₁₃N₅
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of Janus kinase (JAK) inhibitors, particularly in the development of pharmaceuticals targeting inflammatory and autoimmune diseases such as rheumatoid arthritis and psoriasis. Its structure enables selective modulation of JAK enzyme activity, contributing to the efficacy of targeted therapies. Also investigated for potential antitumor activity due to its role in signaling pathway inhibition. Employed in research settings for structure-activity relationship (SAR) studies to optimize drug candidates with improved potency and reduced off-target effects.
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