Used in pharmaceutical research as a key scaffold in the development of kinase inhibitors, particularly for targeting cancer-related proteins such as JAK and FLT3. Its structure enables selective binding to ATP sites in kinases, making it valuable in designing drugs for leukemia and other malignancies. Also explored in inflammatory disease treatments due to its modulation of signaling pathways. Commonly modified to improve solubility, bioavailability, and target specificity in drug candidates.