3-((6-(3-Aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)phenol bis(2,2,2-trifluoroacetate)
98%
Reagent
Code: #192972
CAS Number
1507095-58-0
blur_circular Chemical Specifications
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Molecular Information
Weight
546.38 g/mol
Formula
C₂₂H₁₆F₆N₄O₆
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Registry Numbers
MDL Number
MFCD09037535
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Storage & Handling
Storage
2-8°C, Sealed, Inert Gas
description Product Description
Used in pharmaceutical research as a potent inhibitor of tyrosine kinases, particularly JAK (Janus kinase) and TYK2 pathways, making it relevant in the development of treatments for autoimmune diseases such as rheumatoid arthritis, psoriasis, and inflammatory bowel disease. Its structure allows selective targeting of kinase enzymes involved in cytokine signaling, helping modulate immune responses. Commonly employed in preclinical studies to evaluate efficacy, pharmacokinetics, and safety profiles of kinase inhibitor-based therapies. Also utilized as a reference compound in assay development and high-throughput screening for novel anti-inflammatory agents.
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