4-chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine
≥95%
Reagent
Code: #191855
CAS Number
1830311-70-0
blur_circular Chemical Specifications
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Molecular Information
Weight
409.7907 g/mol
Formula
C₁₈H₂₉BClN₃O₃Si
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Registry Numbers
MDL Number
MFCD30803195
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Physical Properties
Boiling Point
495.0±45.0 °C(Predicted)
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Storage & Handling
Density
1.15±0.1 g/cm3(Predicted)
Storage
2-8°C
description Product Description
Used in pharmaceutical synthesis as a key intermediate in the preparation of kinase inhibitors, particularly for targeted cancer therapies. Its boronate ester functionality enables Suzuki-Miyaura cross-coupling reactions, allowing efficient construction of complex heterocyclic systems found in bioactive molecules. The SEM (trimethylsilylethoxymethyl) protecting group ensures selective reactivity during multi-step synthesis, making it valuable in the development of potent drug candidates targeting oncogenic signaling pathways.
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