2-Chloro-5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-amine
98%
science Other reagents with same CAS 1375301-51-1
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description Product Description
Used as a key intermediate in the synthesis of kinase inhibitors, particularly in the development of anticancer agents. Its structure allows selective binding to ATP sites in protein kinases, making it valuable in targeted therapies for cancers such as leukemia and non-small cell lung carcinoma. Also employed in the preparation of JAK2 and FLT3 inhibitors, where it contributes to modulating signal transduction pathways involved in cell proliferation and survival. Its chloro and amino groups provide reactive handles for further functionalization in medicinal chemistry campaigns.
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