4-Chloro-5-nitro-7H-pyrrolo[2,3-d]pyrimidine
≥95%
Reagent
Code: #161841
CAS Number
22277-01-6
blur_circular Chemical Specifications
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Molecular Information
Weight
198.57 g/mol
Formula
C₆H₃ClN₄O₂
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Registry Numbers
MDL Number
MFCD13183772
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Physical Properties
Boiling Point
434.6°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, stored in inert gas
description Product Description
Used as a key intermediate in the synthesis of kinase inhibitors, particularly in pharmaceutical research targeting cancer therapies. Its structure enables selective binding to enzyme active sites, making it valuable in developing drugs that modulate cell signaling pathways. Commonly employed in the preparation of antitumor agents due to its ability to mimic purine bases in nucleotide-binding pockets. Also utilized in the design of fluorescent probes for biochemical assays, leveraging its nitro and chloro functionalities for further derivatization.
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