(3aR,7aR)-rel-tert-Butyl hexahydro-1H-pyrrolo[3,2-b]pyridine-4(2H)-carboxylate
≥95%
Reagent
Code: #230463
CAS Number
1277168-52-1
blur_circular Chemical Specifications
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Molecular Information
Weight
226.32 g/mol
Formula
C₁₂H₂₂N₂O₂
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Registry Numbers
MDL Number
MFCD22394610
thermostat
Physical Properties
Boiling Point
313.8±15.0°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, protected from light, stored in inert gas
description Product Description
Widely used in pharmaceutical synthesis, this compound serves as a key chiral intermediate in the production of biologically active molecules, particularly in the development of kinase inhibitors and central nervous system agents. Its rigid, stereochemically defined structure makes it valuable for constructing selective drug candidates. It is often employed in asymmetric synthesis to introduce a constrained pyrrolidine-piperidine scaffold, enhancing metabolic stability and target binding affinity. Common applications include its use in route development for APIs where stereocontrol and functional group compatibility are critical.
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