N,N-Dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)methanamine
98%
Reagent
Code: #218574
CAS Number
5654-92-2
blur_circular Chemical Specifications
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Molecular Information
Weight
175.23 g/mol
Formula
C₁₀H₁₃N₃
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Registry Numbers
MDL Number
MFCD01580034
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Physical Properties
Melting Point
144-149 °C
Boiling Point
304.2 °C at 760mmHg
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Storage & Handling
Density
1.155 g/cm3
Storage
2-8°C
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of kinase inhibitors, particularly those targeting JAK (Janus kinase) and TYK2 enzymes involved in inflammatory and autoimmune diseases. Its structure supports binding selectivity, making it valuable in developing treatments for conditions like psoriasis, rheumatoid arthritis, and certain cancers. Also explored in the design of CNS-active agents due to its ability to cross the blood-brain barrier.
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