4,5-Difluoro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine
98%
Reagent
Code: #192650
CAS Number
685513-89-7
blur_circular Chemical Specifications
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Molecular Information
Weight
310.46 g/mol
Formula
C₁₆H₂₄F₂N₂Si
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Registry Numbers
MDL Number
MFCD11616415
thermostat
Physical Properties
Boiling Point
309.4±42.0 °C(Predicted)
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Storage & Handling
Density
1.07±0.1 g/cm3(Predicted)
Storage
-20°C, light-proof, inert gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its structure allows for selective functionalization, making it valuable in constructing complex heterocyclic systems found in bioactive molecules. Commonly employed in medicinal chemistry for SAR studies due to the fluorine atoms enhancing metabolic stability and membrane permeability. Also utilized in the preparation of novel pyrrolopyridine-based drug candidates targeting inflammatory and neurological disorders.
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