1H-Pyrrolo[2,3-b]pyridine, 6-chloro-4-nitro-3-(trifluoroMethyl)-1-[[2-(triMethylsilyl)ethoxy]Methyl]-
95%
Reagent
Code: #191967
CAS Number
892414-51-6
blur_circular Chemical Specifications
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Molecular Information
Weight
395.8368 g/mol
Formula
C₁₄H₁₇ClF₃N₃O₃Si
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Registry Numbers
MDL Number
MFCD26960978
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Physical Properties
Boiling Point
430.0±45.0 °C(Predicted)
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Storage & Handling
Density
1.37±0.1 g/cm3(Predicted)
Storage
2-8°C
description Product Description
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its structure supports selective binding to enzyme active sites, enhancing drug efficacy. The presence of nitro and chloro groups allows further functionalization, enabling derivatization for structure-activity relationship studies. The silyl-protected hydroxyl group provides stability during synthesis and can be deprotected under mild conditions, making it suitable for multi-step reactions. Commonly employed in research settings for designing potent and selective bioactive molecules.
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