4-Fluoro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine
97%
Reagent
Code: #188493
CAS Number
640735-25-7
science Other reagents with same CAS 640735-25-7
blur_circular Chemical Specifications
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Molecular Information
Weight
292.47 g/mol
Formula
C₁₆H₂₅FN₂Si
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Registry Numbers
MDL Number
MFCD11616419
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its structure allows for selective functionalization, making it valuable in constructing complex heterocyclic systems found in bioactive molecules. The silyl protecting group enhances stability during multi-step reactions, while the fluorine atom can influence binding affinity and metabolic resistance in final drug candidates. Commonly employed in medicinal chemistry research for optimizing lead compounds in oncology and inflammatory disease programs.
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