4-Bromo-1-((2-(Trimethylsilyl)Ethoxy)Methyl)-1H-Pyrrolo[2,3-B]Pyridine
95%
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Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its structure allows for selective functionalization, making it valuable in constructing complex heterocyclic systems found in bioactive molecules. Commonly employed in cross-coupling reactions such as Suzuki or Negishi couplings to introduce aryl or heteroaryl groups. The SEM (2-(trimethylsilyl)ethoxymethyl) protecting group on the pyrrole nitrogen enables controlled deprotection and further derivatization, useful in stepwise synthesis of drug candidates. Also applied in medicinal chemistry research for building pyrrolopyridine-based scaffolds with potential antiviral or anti-inflammatory activity.
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