tert-Butyl 1H-pyrrolo[2,3-b]pyridine-1-carboxylate
98%
Reagent
Code: #152816
CAS Number
138343-77-8
blur_circular Chemical Specifications
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Molecular Information
Weight
218.25 g/mol
Formula
C₁₂H₁₄N₂O₂
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Registry Numbers
MDL Number
MFCD08272245
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Storage & Handling
Storage
2-8°C, dry
description Product Description
Used as a protected intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other biologically active molecules. The tert-butoxycarbonyl (Boc) group stabilizes the pyrrolopyridine core during multi-step reactions, allowing selective modification at other sites. It is commonly employed in medicinal chemistry for constructing drug candidates targeting cancer, inflammation, and central nervous system disorders. The protecting group can be easily removed under mild acidic conditions, enabling efficient deprotection without degrading sensitive structures. Its solubility in common organic solvents facilitates use in coupling reactions and heterocycle formation.
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