tert-Butyl 6-bromo-1H-pyrrolo[3,2-b]pyridine-1-carboxylate
96%
Reagent
Code: #151491
CAS Number
1820711-82-7
blur_circular Chemical Specifications
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Molecular Information
Weight
297.15 g/mol
Formula
C₁₂H₁₃BrN₂O₂
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Registry Numbers
MDL Number
MFCD27981330
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Used as an intermediate in pharmaceutical synthesis, particularly in the development of kinase inhibitors and other biologically active compounds. Its protected pyrrolopyridine core allows for selective functionalization, making it valuable in constructing drug candidates targeting cancer, inflammation, and central nervous system disorders. Commonly employed in cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations to introduce aryl or amino groups. The tert-butyl carbamate (Boc) group provides stability during synthesis and can be easily removed under mild acidic conditions to reveal the free amine for further derivatization.
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