tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[3,2-c]pyridine-1-carboxylate
≥95%
Reagent
Code: #148161
CAS Number
877060-60-1
blur_circular Chemical Specifications
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Molecular Information
Weight
344.21 g/mol
Formula
C₁₈H₂₅BN₂O₄
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Registry Numbers
MDL Number
MFCD08234841
thermostat
Physical Properties
Boiling Point
470.1±48.0°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, stored in inert gas
description Product Description
Used in organic synthesis as a boronic ester coupling partner in Suzuki-Miyaura cross-coupling reactions to construct biaryl or heteroaryl frameworks. Its protected pyrrolopyridine core makes it valuable in pharmaceutical and agrochemical research for developing nitrogen-containing heterocyclic compounds. The tert-butyl carbamate group allows for further functionalization or deprotection under mild acidic conditions, enabling sequential synthetic strategies in drug discovery. Commonly employed in the preparation of kinase inhibitors and other bioactive molecules where the pyrrolopyridine scaffold is a key pharmacophore.
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