Tert-butyl 3-(iodomethyl)pyrrolidine-1-carboxylate
96%
Reagent
Code: #65087
CAS Number
479622-36-1
science Other reagents with same CAS 479622-36-1
blur_circular Chemical Specifications
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Molecular Information
Weight
311.16 g/mol
Formula
C₁₀H₁₈INO₂
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Registry Numbers
MDL Number
MFCD08059333
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Physical Properties
Boiling Point
319°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, away from light, dry, sealed
description Product Description
This compound is primarily used in organic synthesis as a versatile intermediate for the construction of complex molecules. Its structure, featuring both a tert-butyl ester group and an iodo-methyl substituent, makes it valuable in the development of pharmaceuticals and bioactive compounds. The iodomethyl group serves as a reactive site for further functionalization, enabling coupling reactions or nucleophilic substitutions. Meanwhile, the tert-butyl ester acts as a protecting group for amines, which can be selectively removed under mild acidic conditions. This chemical is particularly useful in the synthesis of pyrrolidine-based compounds, which are common motifs in drug discovery, such as inhibitors, receptor antagonists, and enzyme modulators. Its application extends to the preparation of peptidomimetics and other biologically active molecules.
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