(2S,4R)-1-Boc-4-(tert-butyldimethylsilyloxy)-2-(hydroxymethyl)pyrrolidine
≥95%
Reagent
Code: #173279
CAS Number
114676-67-4
blur_circular Chemical Specifications
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Molecular Information
Weight
331.52 g/mol
Formula
C₁₆H₃₃NO₄Si
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Registry Numbers
MDL Number
MFCD01862190
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used in the synthesis of complex pharmaceuticals, particularly as a chiral building block in the development of protease inhibitors. Its protected functional groups allow selective deprotection and coupling in multi-step organic syntheses. Commonly employed in the preparation of antiviral agents, including drugs targeting hepatitis C and HIV, due to its ability to mimic peptide bonds and enhance metabolic stability. The silyl and Boc protecting groups provide compatibility with a wide range of reaction conditions, making it valuable in solid-phase and solution-phase peptide synthesis.
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